Publikationen von Prof. Dr. Heisterkamp


  • A. Becker, T. Lehrich, S. Kalies, A. Heisterkamp, A. Ngezahayo (2019): Parameters for optoperforation-induced killing with the C-terminal fragment of Clostridium Perfringens EnterotoxinInternational Journal of Molecular Sciences
  • B. Andrée, H. Ichanti, S. Kalies, A. Heisterkamp, S. Strauß, P.M. Vogt, A. Haverich, A. Hilfiker (2019): Formation of three-dimensional tubular endothelial cell networks under defined serum-free cell culture conditions in human collagen hydrogelsScientific Reports
  • D. Mueller, D. Hagenah, S. Biswanath, M. Coffee, A. Kampmann, R. Zweigerdt, A. Heisterkamp, S. Kalies (2019): Femtosecond laser-based nanosurgery reveals the endogenous regeneration of single Z-discs including physiological consequences for cardiomyocytesScientific Reports
  • M. Machida, T. Niidome, H. Onoe, A. Heisterkamp, M. Terakawa (2019): Spatially-targeted laser fabrication of multi-metal microstructures inside a hydrogelOptics Express
  • S. Johannsmeier, M.L. Torres-Mapa, D. Dipresa, T. Ripken, D Heinemann, A. Heisterkamp (2019): Hydrogels for targeted waveguiding and light diffusionOptics Materials Express, 9, 10, 3925-3940, 2019
  • A. Ingendoh-Tsakmakidis, L. Nolte, A. Winkel, H. Meyer, A. Koroleva, A. Shpichka, T. Ripken, A. Heisterkamp, M. Stiesch (2018): Time resolved 3D live-cell imaging on implantsPloS one
  • B. Bosnjak, M. Permanyer, M.K. Sethi, M. Galla, T. Maetzig, D. Heinemann, S. Willenzon, R. Foerster, A. Heisterkamp, S. Kalies (2018): CRISPR/Cas9 genome editing using gold nanoparticle mediated laserporationAdvanced Biosystems
  • D. Hagenah, A. Heisterkamp, S. Kalies (2018): Effects of cell state and staining on femtosecond laser nanosurgeryJ. Biophotonics, published online first
    DOI: 10.1002/jbio.201700344
  • L. Nolte, G.C. Antonopoulos, L. Raemisch, A. Heisterkamp, T. Ripken, H. Meyer (2018): Enabling second harmonic generation as a contrast mechanism for optical projection tomography (OPT) and scanning laser optical tomography (SLOT)Biomedical Optics Express
  • M. Machida, Y. Nakajima, M.L. Torres, D. Heinemann, A. Heisterkamp, M. Terakawa (2018): Shrinkable silver diffraction grating fabricated inside a hydrogel using 522-nm femtosecond laserScientific Reportsvolume 8, Article number: 187
    DOI: 10.1038/s41598-017-17636-z
  • S. Johannsmeier, P. Heeger, M. Terakawa, S. Kalies, A. Heisterkamp, T. Ripken, D. Heinemann (2018): Gold nanoparticle-mediated laser stimulation induces a complex stress response in neuronal cellsScientific Reports
  • A. Ishii, D. Heinemann, A. Heisterkamp, H. Kanazawa, M. Terakawa (2017): Intracellular localization and delivery of plasmid DNA by biodegradable microsphere-mediated femtosecond laser optoporationJ. Biophotonics, Vol.10, 12, 1723-1731
    DOI: 10.1002/jbio.201600323
  • J. Krawinkel, M.L. Torres, E. Mhatre, A.T. Kovacs, A. Heisterkamp (2017): Structural damage of Bacillus subtilis biofilms using pulsed laser interaction with gold thin filmsJ. Biophotonics, Vol. 10, 8, 1043-1052
    DOI: 10.1002/jbio.201600146
  • K. Doll, E. Fadeeva, J. Schaeske, T. Ehmke, A. Winkel, A. Heisterkamp, B.N. Chichkov, M. Stiesch, N.S. Stumpp (2017): Development of Laser-Structured Liquid-Infused Titanium with Strong Biofilm-Repellent PropertiesACS Appl. Mat. & Interf., 9, 11, 9359-9368
    DOI: 10.1021/acsami.6b16159
  • L. Gentemann, S. Kalies, M. Coffee, H. Meyer, T. Ripken, A. Heisterkamp, R. Zweigerdt, and D. Heinemann (2017): Modulation of cardiomyocyte activity using pulsed laser irradiated gold nanoparticlesBiom. Opt. Expr. 8, 1, 177-192
  • L. Nolte, N. Tinne, J. Schulze, D. Heinemann, G.C. Antonopoulus, H. Meyer, H. Nothwang, T. Lenarz, A. Heisterkamp, A. Warnecke, T. Ripken (2017): Scanning laser optical tomography for in toto imaging of the murine cochleaPlos One, 12, 4, e0175431
  • N. Saklayen, M. Huber, M. Madrid, V. Nuzzo, D. I. Vulis, W. Shen, J. Nelson, A.A. McClelland, A. Heisterkamp, E. Mazur (2017): Intracellular Delivery Using Nanosecond-Laser Excitation of Large-Area Plasmonic SubstratesACS Nano, doi: 10.1021/acsnano.6b08162
    DOI: 10.1021/acsnano.6b08162, 2017
  • N. Saklayen, S. Kalies, M. Madrid, V. Nuzzo, M. Huber, , W. Shen, J. Sinanan-Singh, D. Heinemann, A. Heisterkamp, E. Mazur (2017): Analysis of poration-induced changes in cells from laser-activated plasmonic substratesBiomedical Optics Express, 8, 10, 4756-4771
  • N. Tinne, G.C. Antonopoulus, S. Mohebbi, J. Andrade, L. Nolte, H. Meyer, A. Heisterkamp, O. Majdani, T. Ripken (2017): Three-dimensional hard and soft tissue imaging of the human cochlea by scanning laser optical tomography (SLOT)Plos One, 12, 9, e0184069
  • N. Andric, T. Ehmke, N. Stumpp, T. Ripken, A. Heisterkamp, M. Stiesch (2016): Nonlinear laser scanning microscopy of oral multispecies biofilms: fixative induced fluorescence as a fast and economical in vitro screening methodBioNanoMaterials
    DOI: 10.1515/bnm-2015-0028
  • T. Ehmke, J. Leckelt, M. Reichard, H. Weiss, M. Hovakimyan, A. Heisterkamp, O. Stachs, S. Baltrusch (2016): In vivo nonlinear imaging of corneal structures with special focus on BALB/c and streptozotocin-diabetic Thy1-YFP miceExperimental Eye Research; 146: 137-144
    DOI: 10.1016/j.exer.2015.11.024
  • T. Ehmke, T.G. Seiler, I. Fischinger, T. Ripken, A. Heisterkamp, B.E. Frueh (2016): Comparison of corneal riboflavin gradients using dextran and HPMC solutionsJournal of Refractive Surgery, akzeptiert im August 2016
  • M. Schomaker, D. Heinemann, S. Kalies, S. Willenbrock, S. Wagner, I. Nolte, T. Ripken, H. Murua Escobar, H. Meyer, A. Heisterkamp (2015): Characterization of nanoparticle mediated laser transfection by femtosecond laser pulses for applications in molecular medicinJ. Nanobiotechnology
  • M. Schomaker, D: Killlian, S. Willenbrock, D. Heinemann, S. Kalies, A. Ngezahayo, I. Nolte, T. Ripken, C. Junghanss, H. Meyer, H. Murua Escobar, A. Heisterkamp (2015): Biophysical effects in off-resonant gold nanoparticle mediated (GNOME) laser transfection of cell lines, primary- and stem cells using fs laser pulsesJ. Biophotonics, published online first, DOI: 10.1002/jbio.201400065
    DOI: 10.1002/jbio.201400
  • T. Ehmke, A. Knebl, S. Reiss, I.R. Fischinger, T.G. Seiler, O. Stachs und A. Heisterkamp (2015): Spectral behavior of second harmonic signals from organic and non-organic materials in multiphoton microscopyAIP Advances; 5: 084903
    DOI: 10.1063/1.4915134
  • T. Ehmke, A. Krüger, T. Ripken, S. Reiß, O. Stachs, A. Heisterkamp (2015): Nichtlineare Lasermikroskopie in der Ophthalmologie: Physikalische Prinzipien und wegweisende AnwendungenKlinische Monatsblätter für Augenheilkunde; 232: 1365-1373
  • T.G. Seiler, T. Ehmke, I. Fischinger, D. Zapp, O. Stachs, T. Seiler und A. Heisterkamp (2015): Two-Photon Fluorescence Microscopy for Determination of the Riboflavin Concentration in the Anterior Corneal Stroma when using the Dresden ProtocolInvestigative Ophthalmology & Visual Science; 56(11): 6740-6746
    DOI: 10.1167/iovs.15-17656
  • J. Eberhardt, H. Loewen, A. Krüger, S. Donner, N. Stumpp, M. Patzlaff, O. Stachs, M. Reichard, T. Ripken, A. Heisterkamp, M. Stiesch (2014): Non-invasive in vivo imaging by Confocal Laser Scanning Microscopy of gingival tissues following natural plaque depositionJ. Clin. Periodontol., 2014 Jan 7 [Epub ahead of print] Weitere Informationen
  • L. Gamrad, C. Rehbock, J. Krawinkel, B. Tumursukh, A. Heisterkamp, and S. Barcikowski (2014): Charge Balancing of Model Gold-Nanoparticle-Peptide Conjugates Controlled by the Peptide’s Net Charge and the Ligand to Nanoparticle RatioJ. Phys. Chem. C, 118 (19), 10302–10313
  • S. Kalies, D.Heinemann, M. Schomaker, H. Murua Escobar, A. Heisterkamp, T. Ripken, and H. Meyer (2014): Plasmonic laser treatment for Morpholino oligomer delivery in antisense applicationsJournal of Biophotonics Weitere Informationen
  • S. Kalies, T. Birr, D. Heinemann, M. Schomaker, T. Ripken, A. Heisterkamp, H. Meyer (2014): Enhancement of extracellular molecule uptake in plasmonic laser perforation, J. Biophotonics, 7,7 , 474-482
  • T. Ehmke, A. Knebl, T.H. Nitzsche, A. Heisterkamp (2014): Molecular orientation sensitive second harmonic microscopy by radially and azimuthally polarized lightBiomedical Optics Express; 5(7): 2231-2246
    DOI: 10.1364/BOE.5.002231
  • B. Schlingmann, P. Schadzek, F. Hemmerling, A. Heisterkamp, A. Ngezahayo (2013): The role of the C-terminus in functional expression and internalization of rat connexin46 (rCx46)J. Bioenerg Biomembr., Epub: DOI 10.1007/s10863-012-9480-x
    DOI: 0.1007/s10863-012-9480-x
  • C.A. Mitchell, S. Kalies, T. Cizmár, A. Heisterkamp, L. Torrance, A.G. Roberts, F.J. Gunn-Moore, K. Dholakia (2013): Femtosecond Optoinjection of Intact Tobacco BY-2 Cells Using a Reconfigurable Photoporation PlatformPLoS ONE 8(11): e79235 Weitere Informationen
  • D. Heinemann, M. Schomaker, S. Kalies, M. Schieck, R. Carlson, H. M. Escobar, T. Ripken, H. Meyer, A. Heisterkamp (2013): Gold Nanoparticle Mediated Laser Transfection for Efficient siRNA Mediated Gene Knock DownPLOS ONE, PONE-D-12-40396
  • F. Burgmeister, S. Richter, D. Richter, C. Voigtländer, A. Heisterkamp, S. Nolte (2013): Breakthroughs in Photonics 2012: Femtosecond-Laser NanomachiningIEEE Photonics J., 5, 2, 0700506
  • S. Kalies, T. Birr, D. Heinemann, M. Schomaker, T. Ripken, A. Heisterkamp, H. Meyer (2013): Enhancement of extracellular molecule uptake in plasmonic laser perforationJournal of Biophotonics, doi: 10.1002/jbio.201200200
  • B. Schlingmann, P. Schadzek, S. Busko, A. Heisterkamp, A. Ngezahayo (2012): Cataract-associated D3Y mutation of human connexin46 (hCx46) increases the dye coupling of gap junction channels and suppresses the voltage sensitivity of hemichannelsJ. Bioenerg Biomembr., Epub: DOI: 10.1007/s10863-012-9461-0
    DOI: 10.1007/s10863-012-9461-0
  • H.A. Rendall, R.F. Marchington, B.B. Praveen, G. Bergmann, Y. Arita, A. Heisterkamp, F.J. Gunn-Moore and K. Dholakia (2012): High-throughput optical injection of mammalian cells using a Bessel light beamLab on a Chip, Epub: DOI: 10.1039/c2lc40708f
    DOI: 10.1039/c2lc4
  • M. Kellner, M. Heidrich, R. Beigel, R.-A. Lorbeer L. Knudsen, T. Ripken, A. Heisterkamp, H. Meyer, M.P. Kühnel, M. Ochs (2012): Imaging of the mouse lung with scanning laser optical tomography (SLOT)Journal of Applied Physiology, vol. 13
  • R. Eickhoff, R.-A. Lorbeer, H. Scheiblich, A. Heisterkamp, H. Meyer, M. Stern, G. Bicker (2012): Scanning Laser Optical Tomography Resolves Structural Plasticity during Regeneration in an Insect BrainPloS ONE,Volume 7 | Issue 7 | e41236
  • S. Willenbrock, O. Braun, J. Baumgart, S. Lange, C. Junghanss, A. Heisterkamp, I. Nolte, J. Bullerdieck, H. Murua Escobar (2012): TNF-a induced secretion of HMGB1 from non-immune canine mammary epithelial cells (MTH53A)Cytokine, 57, 2, 210-20
  • A. Krüger, M. Hovakimyan, D.F. Ramírez Ojeda, O. Stachs, A. Wree, R.F. Guthoff and A. Heisterkamp (2011): Combined Nonlinear and Femtosecond Confocal Laser-Scanning Microscopy of Rabbit Corneas after Photochemical Cross-LinkingInvest. Ophthalmol. Vis. Sci. June 16, 2011 vol. 52 no. 7 4247-4255
  • G. Kensah, I. Gruh, J. Viering, H. Schumann, J. Dahlmann, H. Meyer, D. Skvorc, A. Bär, P. Akhyari, A. Heisterkamp, A. Haverich, U. Martin (2011): A Novel Miniaturized Multimodal Bioreactor for Continuous In Situ Assessment of Bioartificial Cardiac Tissue During Stimulation and MaturationTissue Eng Part C Methods; 17(4): 463–473
  • K. Kütemeyer, A. Lucas-Hahn, B. Petersen, H. Niemann, A. Heisterkamp (2011): Femtosecond laser-induced fusion of nonadherent cells and two-cell porcine embryos, Journal of Biomedical Optics, Vol. 16, No. 8, 088001
  • K. Kütemeyer, G. Kensah, M. Heidrich, H. Meyer, U. Martin, I. Gruh, A. Heisterkamp (2011): Two-photon induced collagen-crosslinking in bioartificial cardiac tissue, Optics Express, Vol. 19, No. 7, 15996-16007
  • K. Kütemeyer, G. Kensah, M. Heidrich, H. Meyer, U. Martin, I. Gruh, A. Heisterkamp (2011): Two-photon induced collagen cross-linking in bioartificial cardiac tissueOptics Express, Vol. 19, Issue 17, pp. 15996-16007
  • M. Heidrich, M. P. Kühnel, M. Kellner, R.-A. Lorbeer, T. Lange, A. Winkel, M. Stiesch, H. Meyer, and A. Heisterkamp (2011): 3D imaging of biofilms on implants by detection of scattered light with a scanning laser optical tomographBiomedical Optics Express, Vol. 2, Issue 11, pp. 2982-2994 (2011)
  • M. Heidrich, M.P. Kühnel, M. Kellner, R.-A. Lorbeer, T. Lange, A. Winkel, M. Stiesch, H. Meyer, A. Heisterkamp (2011): 3D imaging of biofilms on implants by detection of scattered light with a scanning laser optical tomographBiomed. Opt. Exp., Vol.2, Issue 11, pp. 2982-2994
  • M. Hovakimyan, R. Guthoff, S. Knappe, A. Zhivov, A. Wree, A. Krüger, A. Heisterkamp, O. Stachs (2011): Short-Term Corneal Response to Cross-Linking in Rabbit Eyes Assessed by In Vivo Confocal Laser Scanning Microscopy and HistologyCornea, February 2011 - Volume 30 - Issue 2 - pp 196-203
  • M. Pangalos, W. Bintig, B. Schlingmann, F. Feyerabend, F. Witte, D. Begandt, A. Heisterkamp, A. Ngezahayo (2011): Action potentials in primary osteoblasts and in the MG-63 osteoblast-like cell lineJ. Bioenergetics and Biomembranes, 43, 3, 311-322
    DOI: 10.1007/s10863-011-9354-7
  • M. Pospiech, M. Emons, K. Kütemeyer, A. Heisterkamp, U. Morgner (2011): Superresolved femtosecond laser nanosurgery of cells, Biomedical Optics Express, Vol. 2, No. 2, 264-270
  • R.-A. Lorbeer, M. Heidrich, C. Lorbeer, D.F. Ramírez Ojeda, G. Bicker, H. Meyer, and A. Heisterkamp (2011): Highly efficient 3D fluorescence microscopy with a scanning laser optical tomographOpt. Express, Vol. 19 Issue 6, pp.5419-5430
  • S. Kalies, K. Kütemeyer, A. Heisterkamp (2011): Mechanisms of high-order photobleaching and its relationship to intracellular ablationBiomedical Optics Express, Vol. 2, No. 4, 805-816
  • J. Baumgart, W. Bintig, A. Ngezahayo, H. Lubatschowski, and A. Heisterkamp (2010): Fs-laser-induced Ca2+ concentration change during membrane perforation for cell transfectionOptics Express, 18, 3, 2219 | Datei |
  • K. Kütemeyer, A. Lucas-Hahn, B. Petersen, P. Hassel, E. Lemme, H. Niemann, A. Heisterkamp (2010): Combined multiphoton imaging and automated functional enucleation of porcine oocytes using femtosecond laser pulses, Journal of Biomedical Optics, Vol. 15, Issue 4, 046006 Weitere Informationen
  • K. Kütemeyer, R. Rezgui, H. Lubatschowski, A. Heisterkamp (2010): Influence of laser parameters and staining on femtosecond laser-based intracellular nanosurgery, Biomedical Optics Express, Vol. 1, No. 2, 587-597 Weitere Informationen
  • A. Krüger, M. Hovakimyan, DF. Ramirez, O. Stachs, H. Lubatschowski, A. Wree, R. Guthoff A. Heisterkamp (2009): Two-Photon Microscopy of the Cornea using Intrinsic ContrastKlin. Mon. Augenhlkd, 226 (12), 970-979, 2009
  • J. Baumgart, K. Kütemeyer, W. Bintig, A. Ngezahayo, W. Ertmer, H. Lubatschowski, and A. Heisterkamp (2009): Repetition rate dependency of reactive oxygen species formation during femtosecond laser based cell surgeryJ. of Biomedical Optics, Vol. 14, 054040 Weitere Informationen
  • K. Kütemeyer, J. Baumgart, H. Lubatschowski, A. Heisterkamp (2009): Repetition rate dependency of low-density plasma effects during femtosecond-laser-based surgery of biological tissue, Applied Physics B, Vol. 97, No. 3, 695-699 Weitere Informationen
  • O. Stachs, S. Schumacher, M. Hovakimyan, M. Fromm, A. Heisterkamp, H. Lubatschowski, R. Guthoff (2009): Visualization of fs laser pulse induced micro-incisions inside crystalline lens tissue, J. Catarc. Refract. Surg. 35, 11, 1979, 2009
  • J. Baumgart, W. Bintig, A. Ngezahayo, S. Willenbrock, H. Murua Escobar, W. Ertmer, H. Lubatschowski, A. Heisterkamp (2008): Quantified femtosecond laser based opto-perforation of living GFSHR-17 and MTH53a cellsOPTICS EXPRESS
  • J. Baumgart, W. Bintig, A. Ngezahayo, S. Willenbrock, H. Murua Escobar, W. Ertmer, H. Lubatschowski, A. Heisterkamp (2008): Quantified femtosecond laser based opto-perforation of living GFSHR-17 and MTH53a cells OPTICS EXPRESS, Vol. 16, No. 5, 3021-3031 Weitere Informationen
  • C.L. Arnold, A. Heisterkamp, W. Ertmer, H. Lubatschowski (2007): Computational model for nonlinear plasma formation in high NA micromachining of transparent materials and biological cellsOPTICS EXPRESS, Vol. 15, No. 16, 10303
  • S. Kumar, I.Z. Maxwell, A. Heisterkamp, T.R. Polte, T. Lele, M. Salanga, E. Mazur, D.E. Ingber (2006): Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization and extracellular matrix mechanics.Biophys. Journal, 90, 3762-3773
  • A. Heisterkamp, I. Z. Maxwell, E. Mazur, J. M. Underwood, J. A. Nickerson, S. Kumar, D. E. Ingber (2005): Pulse energy dependence of subcellular dissection by femtosecond laser pulsesOpt. Express 13, 3690-3696
  • C.L. Arnold, A. Heisterkamp, W. Ertmer, H. Lubatschowski (2005): Streak formation as side effect of optical breakdown during processing the bulk of transparent Kerr media with ultra-short laser pulses Appl. Phys. B. 80, 247-253
  • R.R. Krueger, J. Kuszak, H. Lubatschowski, R. Myers, T. Ripken, A. Heisterkamp (2005): First Safety Study of Femtosecond Laser Photodisruption in Animal Lenses: Tissue Morphology and Cataractogenesis J Cataract Refract Surg. 31(12):2386-94
  • A. Heisterkamp, T. Mamom, H. Lubatschowski, W. Drommer, O. Kermani, H. Welling, W. Ertmer (2003): Application of Ultrashort Laser Pulses in Living AnimalsGraefe's Arch. Clin. Exp. Opthal., 241 (6), 511 – 517
  • A. Heisterkamp, T. Mamom, W. Drommer, W. Ertmer, and H. Lubatschowski (2003): Photodisruption with Ultrashort Laser Pulses for Intrastromal Refractive SurgeryInternational Journal of Laser Physics, Vol. 13, 5, p. 743, (Invited Paper)
  • A. Heisterkamp, T. Ripken, T. Mamom, W. Drommer, H. Welling, W. Ertmer, H. Lubatschowski (2002): Nonlinear Side-Effects of fs-Pulses Inside Corneal Tissue During PhotodisruptionAppl. Phys. B, 74, 1-7
  • H. Lubatschowski, A. Heisterkamp, W. Drommer, O. Kermani, H. Welling, W. Ertmer. (2002): Intrastromal Refractive Surgery using Ultrashort Laser Pulses Med. Laser Appl. 17, 1, 4-8, 2002
  • A. Heisterkamp, G. Maatz, U. Hetzel, W. Drommer, H. Lubatschowski, H., Welling, W. Ertmer (2001): Optimierung der Laserparameter für die Intrastromale Schnittführung mittels Ultrakurzer Laserpulse Ophthalmologe 98, 623-628
  • H. Lubatschowski, A. Heisterkamp, W. Drommer, O. Kermani, H. Welling, W. Ertmer. (2001): Application of Ultrashort Laser Pulses for Refractive Surgery of the Eye LaserOpto, 33, (6), 40-46
  • G. Maatz, A. Heisterkamp, H. Lubatschowski, S. Barcikowski, C. Fallnich, H. Welling, W. Ertmer (2000): Chemical and Physical Side Effects at Applications of Ultrashort Laser Pulses for Intrastromal Refractive Surgery J. Opt. A 2, 59-64
  • H. Lubatschowski, G. Maatz, A. Heisterkamp, U. Hetzel, W. Drommer, H. Welling, W. Ertmer. (2000): Application of Ultrashort Laser Pulses for Intrastromal Refractive Surgery Graefe's Arch. Clin. Exp. Ophthal., 238, 33-39